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Should VAS Infrastructure Limited (531574) be sold ✌️【Stock Trading】✌️ Free stock data analysis tools to help you select stocks accurately and capture global market trends. Stay ahead with expert market predictions for better investment returns. As the co-founder of Wild Instincts animal rescue in Wisconsin’s Northwoods, Naniot and his team spent the season sweating in gloves, gowns, smocks and masks and going through what felt like endless rounds of disinfection as they moved between the cages of the sick and injured animals they cared for.

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“Influenza actually makes mutations, in the sense of making errors copying its genome, at a higher rate than a coronavirus like SARS-CoV2,” said Dr. Jesse Bloom, a computational biologist who focuses on influenza viruses at the Fred Hutch Cancer Center in Seattle.

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If humans happen to be that environment, and H5N1 changes at the right place at the right time, suddenly the animal pandemic could become a major problem for people, too.

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“They would have these severe, severe seizures,” Naniotsaid. “Screaming very loud, whole-body tremors.”

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“The severity of the seizures is something I really hadn’t seen before,” Naniot said. “It’s a very sad thing to see, the progression of the disease.”

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“We call these dead-end infections,” said Dr. Scott Weese, a veterinarian and expert in zoonotic infections, at the University of Guelph in Canada.

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Using a strain of H5N1 from the recent cattle outbreak,scientists recently confirmed that this version of the virus is unlikely to transmit through the air. In experiments with ferrets, which are considered the gold standard for studying how viruses transmit in people, researchers at the US Centers for Disease Control and Prevention grew a sample of the same H5N1 virus taken from afarmworker with the fluin Texas to experimentally infect six of the animals. Then, three healthy ferrets were placed in the same enclosures with three of the sick animals. These animals could touch, nose and lick the sick animals, and all of them became ill.

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“It’s really important to understand everything we know today is a snapshot of today, and these viruses can change very quickly,” said Dr. Rick Bright, an immunologist and former director of the US Biomedical Advanced Research and Development Authority in an interview with 【 - Free Trading Strategy Suggestions 】 Chief Medical Correspondent Dr. Sanjay Gupta for theChasing Lifepodcast.

“They can adapt, and they can spread very easily when they do change,” said Bright, who is now CEO of Bright Global Health.

Dr. Erin Sorrell, a virologist and a senior scholar at the Johns Hopkins Center for Health Security, says that while humans have been exposed to seasonal strains of the flu, and flu vaccines help build immunity H1 and H3 flu strains, H5N1 would look pretty different to our bodies.

“Our existing immunity to H3 and H1 is not necessarily going to protect us against exposure to an H5 virus,” she said.

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“While the three cases of A(H5N1) in the United States have been mild, it is possible that there will be serious illnesses among people,” the CDC wrote in its conclusions on the study.

In the more thantwo dozen human infectionswith H5N1 virus worldwide since 2022, with the most recent iteration of the virus, there’s been a wide spectrum of severity. Fourteen illnesses were severe or critical, seven were fatal, sixwere mild and eight didn’t have any symptoms at all,according to the CDC.

Dr. Seema Lakdawala, a microbiologist and immunologist at Emory University who specializes in the flu, thinks the difference in symptom severity may be due to previous exposure to seasonal viruses. Herexperiments in ferretssuggest that our bodies wouldn’t necessarily be totally defenseless.  In her lab, ferrets with previous exposures to seasonal flu strains didn’t get as sick when exposed to new flu viruses compared to those with no prior exposure to seasonal strains.  She says she hasn’t tested this with any of the strains involved in the cattle outbreak, however.

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How much help we might get from past exposures to flu viruses is difficult to predict, however, which is why vaccination would still be important to tune up our immunity.

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Finland has already ordered 20,000 doses of a different H5 strain — H5N8 — which, will be used as soon as they’re available to protect workers who might be vulnerable to the virus, such as scientists and thosein direct contact with infected animalson mink farms, local officials told health and science news outlet, STAT News.

For now, the CDC maintains its assessment that the risk to the general public from H5N1 is low, though people who work with infected animals have a higher risk and should wear protective clothing and take additional precautions to avoid getting sick. The Administration for Strategic Preparedness and Response, or ASPR, has made that protective equipment available to states for use on farms, and the USDA has made additional funding available to farms to support efforts to safeguard their livestock from disease.

But so far, wearing this equipment is voluntary, and there are concerns that it might be difficult for farm workers to wear the fullrecommended kit, which includes coveralls, an apron, a mask, eye protection, a head covering, gloves and boots during the summer, which is again expected to break heat records.

Bright thinks severity of symptoms may depend on how much virus a person is exposed to when they are infected. Touching contaminated milk or the body of a dead bird and then rubbing your eyes or nose might deliver a smaller dose of the virus, and ultimately result in milder symptoms. Whereas ingesting large amount of virus — as some animals do when they scavenge for food or as humans in some countries do when consuming dishes made with duck blood — could lead to severe disease.

“The virus is able to infect a number of internal organs. So it doesn’t just locate, say, in the lungs, as we would think most influenza viruses would,” Bright said. It’s also been found in “the brains and then the spleens, the intestines, and the heart and throughout the body of those animals.”

Dr. Richard Webby, who directs the WHO’s Collaborating Centreon the Ecology of Influenza in Animals and Birdsat St. Jude Children’s Research Hospital, agrees.

“It’s at the top of the list in terms of bad guy viruses,” he said, noting that the virus is nerve-loving, or neurotropic. “So it goes to the brain and causes very, very severe disease.”

Infected animals often behave strangely or aggressively. Ducks waddle in circles, twisting their necks, writhing on the ground.

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“I’ve been a student of this virus. And I surely have been amazed at how it’s changed over the course of the last 20-some years, but at the same time, you know, I’m looking for evidence that it is likely to become a virus infecting humans and then transmitted by humans to other humans. And we just haven’t seen that yet,” he added.

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Other rescue organizations in their network had a few foxes infected with H5N1 that survived, but they ultimately went blind.

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“Unfortunately, it’s kind of like when Covid went through, you know, it first started someplace,” he said.

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