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“We thought we were doing everything we could to avoid anything like this from happening,” the center’s director and cofounder Mark Mathews told 【 - Free Access to Community 】. “The cats are pretty well split up into 30- by 40-foot habitats.”

It is currently unknown exactly how the big cats contracted bird flu, but Mathews said the first death occurred around Thanksgiving.

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“Tabbi the tiger was a fun-loving tiger. She had a super personality. Every time I’d come up, she’d be running to meet me,” Mathews said.

Only 17 of the 37 cats once housed at the sanctuary are left. Neiko, an African serval, is still in critical condition fighting to regain the use of his back legs, according to Mathews.

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“Initially, we thought it was bird droppings from water foul,” Mathews said. “We are in a flight pattern for migratory birds; not sure if that’s part of the equation or not. We really don’t know if it is food-related or not.”

Cats are particularly vulnerable to bird flu, which can cause subtle initial symptoms that may “progress rapidly, often resulting in death within 24 hours due to pneumonia-like conditions,” the center said. Symptoms include low energy, swelling of body parts, lack of coordination and diarrhea in pet birds, while cats and dogs may experience a fever, lethargy and low appetite, among other symptoms, according to theAmerican Veterinary Medical Association.

“Usually, when a vet comes out and they do immobilization, they start to feel better, and with Harley (the cougar), it was different because he made it pretty obvious he wasn’t feeling better after his treatment,” sanctuary employee Jolie Connolly-Poe told 【 - Free Access to Community 】 affiliateKOMO.

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“(I’m) feeling devastated, kind of in shock. It just feels terrible that you take such good care of them, and then something unforeseen takes its toll real fast,” Connolly-Poe said. The center is “just taking good care of those recovering.”

In the 20 years since the sanctuary opened, Mathews told KOMO there hasn’t been an instance like this before. The center is taking additional precautions to avoid a further spread of bird flu as they prepare to disinfect everything.

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CORRECTION: An earlier version of this story undercounted the number of cases of human exposure to bird flu from animals.

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