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Don’t just call it laziness: After a long period of thinking hard, making decisions that favor ease in the short term but are worse overall appears to be a biological regulation tool to combat cognitive fatigue, according toa new study published Thursday in the journal Current Biology.

“Influential theories suggested that fatigue is a sort of illusion cooked up by the brain to make us stop whatever we are doing and turn to a more gratifying activity,” said study author Mathias Pessiglione, Inserm research director at the Brain and Spine Institute in Paris, in a news release. “Our findings show that cognitive work results in a true functional alteration — accumulation of noxious substances — so fatigue would indeed be a signal that makes us stop working, but for a different purpose: to preserve the integrity of brain functioning.”

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In the study, 40 people were given either an easy or hard version of a task that involved differentiating letters on a screen for more than six hours. The participants reported their levels of fatigue, and researchers used magnetic resonance spectroscopy (MRS) to monitor their metabolic response throughout the study period, according to the study.

Each participant was then offered choices of either an immediately gratifying smaller reward that required less cognitive control or one that was higher value in the longer term but involved some impulse control (for example, I’ll give you $10 now or transfer $50 into your bank account tomorrow).

Participants who had to think harder for the six-hour task were more likely to take the smaller reward, according to the study. The researchers found that the harder the participants thought, the higher their levels ofglutamate, a neurotransmitter that works in memory and learning.

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If you are about to make an important decision or trying to keep the chores from piling up, it’s important to make sure you aren’t too tired, said study author Antonius Wiehler, a cognitive neuroscientist and postdoctoral researcher at the Paris Brain Institute.

But bad news: It may also be difficult for people to accurately gauge how fatigued they actually are, according to the study.

You are less likely to become cognitively fatigued by an activity you enjoy than one you don’t, said Phillip Ackerman, a professor of psychology at the Georgia Institute of Technology. Ackerman was not involved in the study.

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In the best-case scenario, people can avoid cognitive fatigue by building in breaks during the difficult thinking, Ackerman said.

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“I would employ good old recipes: rest and sleep! There is good evidence that glutamate is eliminated from synapses during sleep,” he said in the release.

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