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But she added that research has been less clear on whether lowering blood pressure in older adults would reduce that risk.

“What is so exciting about our study is that the data shows that those people who were taking the blood pressure lowering medication had a lower risk of a dementia diagnosis than those taking a matching placebo,” said Peters, who is also a senior research scientist at Neuroscience Research Australia, a nonprofit research organization.

Blood pressure is measured in units of millimeters of mercury (abbreviated as mmHg), which consists of two numbers: an upper or systolic reading that represents the maximum amount of pressure in your arteries, and the lower or diastolic reading that shows the pressure in your arteries when your heart muscle is at rest between beats.

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Each of the clinical trials compared people taking blood pressure medications withpeople taking a matching placebo pill and followed them for an average of 4.3 years. Pooling the data, Peters and her team found that a drop of about 10 mm/Hg on the systolic and 4 mm/Hgon the diastolic blood pressure readings at 12 months significantly lowered the risk of a dementia diagnosis.

In addition, there was a broad linear relationship: As blood pressure dropped, so did cognitive risk, which held true until at least 100 mm/Hg systolic and 70 mm/Hg diastolic, the study said. There was also no sign that blood pressure medications may harm blood flow into the brain at later ages.

“We know that what we do throughout life is likely to have an impact on brain health in late life,” Peters said. “So the best advice we can give is to lead a healthy lifestyle at all ages, and of course, if you are prescribed medication to control your blood pressure to take it according to the instructions from your doctor.”

Lifestyle changes can add to or in some cases replace the need for hypertension medications,according to the American Heart Association. Suggested actions include limiting alcohol, managing stress, stopping smoking, eating a well-balanced and low-salt diet, getting plenty of exercise and sleep, and taking blood pressure medications as directed.

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In one 16-week study published in 2018, people who went on a low-salt diet, exercised and practiced weight management techniques (such as watching portion sizes) lowered their blood pressure by an average16 mmHg systolic and 10 mmHg diastolic, the American Heart Associationsaid.

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However, if lifestyle changes don’t significantly lower blood pressure within six months,the American Heart Association recommendsadding hypertension prescription medications while continuing the healthy behaviors.

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