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Just how do they do that? It could all come down to good genes, according to a new studypublishedby The Royal Society.

“The odds of developing cancer increase with longevity and body mass,” explained lead study author Daniela Tejada-Martinez, a postdoctoral researcher at Thomas Jefferson University in Philadelphia.

Having more cells means having a higher probability that some of them may develop dangerous mutations as they grow and divide over the course of their life cycle.

“Paradoxically, big and/or long-lived species have lower cancer risk. However, the cetacean’s mechanisms against cancer and aging remain a mystery,” Tejada-Martinez said.

Her research, aimed at solving that mystery, suggests cetaceans could have evolved “additional mechanisms” to protect against such diseases like cancer, according to Tejada-Martinez.

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“Cetaceans are an amazing model for ageing and disease resistance research, since they are the longest-living mammals. Some cetaceans, like the bowhead whale, can live over 200 years,” she said via email.

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Understanding how whales protect themselves against cancer could help humans make strides against the disease, which killed anestimated10 million people worldwide in 2020.

“Cancer is the original problem of multicellularity, and it is clear across numerous studies that nature has beat cancer in a myriad of ways in order to increase the fitness of organisms over the history of life,” said Marc Tollis, an assistant professor at Northern Arizona University.

“Since cancer is a body-size and age related disease, the search for whale-specific changes in protein coding genes that are linked to human cancers can help target potential human cancer therapies,” he explained.

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“The study of medical conditions under an evolutionary perspective leads to a better understanding about how other species can fight diseases more efficiently than us,” Tejada-Martinez said.

“The discovery of new molecular variants, including additional copies of important regulatory genes, could lead to the creation of innovative treatments for cancer and age-related diseases,” she added.

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